Quantitative Trait Loci (QTL)-Guided Metabolic Engineering of a Complex Trait

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Quantitative Trait Loci (QTL)-Guided Metabolic Engineering of a Complex Trait.

Engineering complex phenotypes for industrial and synthetic biology applications is difficult and often confounds rational design. Bioethanol production from lignocellulosic feedstocks is a complex trait that requires multiple host systems to utilize, detoxify, and metabolize a mixture of sugars and inhibitors present in plant hydrolysates. Here, we demonstrate an integrated approach to discove...

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QTL-guided metabolic engineering of a complex trait

Engineering complex phenotypes for industrial and synthetic biology applications is difficult and often confounds rational design. Bioethanol production from lignocellulosic feedstocks is a complex trait that requires multiple host systems to utilize, detoxify, and metabolize a mixture of sugars and inhibitors present in plant hydrolysates. Here, we demonstrate an integrated approach to discove...

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ژورنال

عنوان ژورنال: ACS Synthetic Biology

سال: 2016

ISSN: 2161-5063,2161-5063

DOI: 10.1021/acssynbio.6b00264